First, have a definite, clear practical ideal; a goal, an objective. Second, have the necessary means to achieve your ends; wisdom, money, materials, and methods. Third, adjust all your means to that end.

Aristotle

We must believe that we are gifted for something, and that this thing, at whatever cost, must be attained.

Marie Curie

It is never too late to be what you might have been.

George Eliot